Post myocardial infarction depression, prevalence, diagnosis, pathophysiologic mechanisms, treatment and management

Year: 2024; Volume: 4; Issue: 3Page No: 15 – 21

Article Type:  Short Communication

Authors:  Bayan Omar Sharif *1,   Nazdar Qudrat Abas 2, Peshin Abdalstar Salih3, Talar Jamal Rahim4, Shahla Hamid Hassan5

https://doi.org/10.55349/ijmsnr.2024431521

Affiliations:  *1Health Development and Training Center, Sulaimani Directorate of Health, Sulaimani, Kurdistan Region, Iraq.  Email ID: omerbayn82@gmail.com
2Department of Psychology, College of Education, University of Garmian.  Email ID:  nazdar.qudrat@garmian.edu.krd

3The British International School of Sulaymani. Iraq,  Email ID: peshinsaleh@gmail.com

4Sulaimani Directorate of Health, Sulaimani, Kurdistan Region, Iraq, Sulaimani Burn & Plastic Surgery Hospital.  Email ID:  talar.138193@gmail.com

5Sulaimani Directorate of Health, Kurdistan Region, Iraq, Soz mental hospital.  Email ID:  shahlahamid81@gmail.com

How to cite this article:  Sharif OB, Abas NQ, Salih PA, Rahim TJ, Hassan SH. Post myocardial infarction depression, prevalence, diagnosis, pathophysiologic mechanisms, treatment and management.   Int J Med Sci and Nurs Res 2024;4(3):15–21      DOI: 10.55349/ijmsnr.2024431521

Article Summary:  Submitted: 10-July-2024   Revised: 30-July-2024   Accepted: 21-August-2024    Published: 30-September -2024


Abstract

Background: Myocardial infarction (MI) can have significant physical and mental consequences. Depression is a prevalent psychiatric condition after MI which can reduce the quality of life and increase the mortality rates of patients. The link between depression and poor cardiac outcomes has prompted clinical trials investigating the impact of treating depression on both outcomes.

Methods: In this paper, we discussed about post Myocardial infarction depression, its Prevalence, pathophysiologic mechanisms, such as neurobiological mechanisms of post-MI depression, Hypothalamic-pituitary-adrenal axis and autonomic nervous system, environmental factors, like lack of social support, lifestyle changes, economic status and health related anxiety.

Results: By 2030, depressive disorders are projected to become the first leading cause of disease burden in high-income countries and the second leading cause globally. Depression is prospectively linked to negative cardiac outcomes, regardless of other cardiovascular risk factors. In individuals who are initially healthy, depression is correlated with a greater likelihood of developing heart disease compared to those without depression.

Conclusion: We have concluded that several factors including the dysregulation of the autonomic nervous system and Hypothalamic-pituitary-adrenal axis, various environmental factors, and genetics can be contributed to the correlation between Myocardial infarction and depression.

Keywords: Post myocardial infarction, depression, prevalence, diagnosis, pathophysiologic mechanisms, treatment, management

Source of funding: None

Conflict of Interest: Nothing to declared by the authors

Corresponding Author:

Dr. Bayan Omar Sharif, M.Sc. (N), Ph.D.,

Health Development and Training Center,

Sulaimani Directorate of Health,

Sulaimani,

Kurdistan Region,

Iraq.

Email ID: omerbayn82@gmail.com


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